Increased intestinal permeability is another term for the digestive disorder known as “leaky gut syndrome,” in which bacteria and toxins “leak” through the intestinal lining.
Many doctors and healthcare providers do not recognize leaky gut syndrome (LGS) as a medical condition. However, recent scientific evidence indicates that a leaky gut may play a role in various medical conditions.
This article is about the causes, symptoms, and treatment of the leaky gut syndrome.
What is leaky gut syndrome?
The human digestive tract is the location of food breakdown and nutrient absorption.
Additionally, the digestive system is essential in protecting the body from harmful substances. The intestines’ walls act as filters, limiting what enters the bloodstream and is transported to your organs.
Allowing water and nutrients to pass through while preventing harmful substances from passing through the intestinal wall are known as tight junctions. Permeability of the intestinal wall is referred to as intestinal permeability.
A more permeable gut could allow bacteria and toxins from the gut to enter the bloodstream, resulting in an increased risk of disease. This condition is referred to as having a “leaky gut.”
When bacteria and toxins enter the bloodstream through a “leaky” gut, it can lead to widespread inflammation and, possibly, an immune system reaction.
Are there signs and symptoms?
Each person’s experience with leaky gut will be unique, as will their symptoms. Such as:
- Celiac disease can lead to a variety of symptoms, including bloating and gas, fatigue, nausea, and vomiting.
- Inflammatory bowel disease (IBD) is associated with abdominal pain, diarrhea, weight loss, fatigue, fever, and bloody stool, among other symptoms.
- Symptoms of IBS include cramping and pain in the lower abdomen, bloating, mucus in the stool, and excessive gas in the digestive tract.
Risk factors and causes
Experts are still unsure of the exact cause of leaky gut syndrome. Numerous risk factors can disrupt the gut microbiota and contribute to an increase in IP. Following are some of the examples:
- nutritional deficiencies
- alcoholic beverage consumption
- autoimmune diseases, including lupus
The mannitol and lactulose test are the most commonly used method for diagnosing leaky gut syndrome. They are both water-soluble molecules that the body can’t use. Healthy intestines allow Mannitol to be easily absorbed.
Despite its size, lactulose is only partially absorbed.
Mannitol and lactulose may add to a solution for the test. It is necessary to collect urine for six hours to determine how much of each substance may absorb by the body. In a healthy person, mannitol levels are high and lactulose levels are low. It may become a sign of a leaky gut when both molecules may find in high concentrations. Deficiencies in both molecules indicate a general lack of nutrient absorption in the body.
How to heal leaky gut?
Treatment recommendations from your doctor may likely to customize to your specific diagnosis, which may include leaky gut as a symptom. For instance:
If you may diagnose with celiac disease, a gluten-free diet may aid in the healing process.
The gut lining may heal if you take anti-inflammatory prescription medication, immune system suppressors, antibiotics, pain relievers, and supplements like iron, calcium, and vitamin D after being diagnosed with IBD.
If you may diagnose with IBS, anticholinergic medications, tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), antidepressants, antibiotics, and pain relievers. Also, medications specifically for IBS (alosetron, lubiprostone, and linaclotide), may help alleviate your symptoms.
Is it possible to make dietary changes to help with leaky gut syndrome?
Leaky gut diets target the underlying cause of the condition. Celiac disease and non-celiac gluten sensitivity can both become helped by eliminating all gluten-containing foods from your diet.
Since an unbalanced gut microbiome may link to leaky gut, changing your diet may help you achieve this balance. Again, it’s unclear if this has any effect on the disease caused by a leaky gut.
The gut bacteria can become unhealthier if you consume a lot of sugar, saturated fats, and animal proteins in your diet. Eating foods high in fiber and healthy fats, such as the Mediterranean Diet (which restricts red meat and sugar) can help restore the balance of good bacteria in the gut. Gut bacteria produce short-chain fatty acids from fiber and prebiotics. Digestive health benefits from these acids are numerous. Adding these fatty acids to your diet can help to keep your digestive system healthy. So, Probiotics may show to aid in the restoration of the gut lining.
There may a danger in going on extreme diets or taking supplements that claim to cure leaky gut. Thus, Supplements can cause side effects, and removing foods can cause nutritional deficiencies.
If you notice an unusual symptom in your body, you should see a healthcare professional immediately. So, You can order any medicines prescribed to you from a pharmacy online.
Who is at risk of developing a leaky gut?
As this barrier may not completely impenetrable (and it may not suppose to be!), we all have some degree of leaky gut. A genetic predisposition may play a role, but it’s not the only factor. Modern life and poor lifestyle effects may become the primary cause of gut inflammation. Thus, There is substantial evidence that the standard American diet, which is deficient in fiber and excessive in sugar and saturated fats, may be the catalyst for this process. So, This equilibrium appears to throw off by things like binge drinking and high levels of stress.
In conditions like celiac disease, Crohn’s disease, and irritable bowel syndrome, increased intestinal permeability is a contributing factor. Thus, The most important question may whether or not a leaky gut can cause problems elsewhere in the human body. Hence, Other autoimmune diseases (lupus, type 1 diabetes, multiple sclerosis, allergies, asthma, acne, obesity, and even mental illness) may link to leaky gut in some studies. However, we don’t yet have human clinical trials to support this theory.
Self-care measures that promote overall digestive health may become the most effective way to guard against leaky gut:
- Increase your intake of foods high in fiber. The soluble fiber found in vegetables, legumes, and fruit help your gut’s beneficial bacteria thrive.
- Consume fewer refined carbohydrates. Too much sugar can impair gut barrier function.
- Reduce your NSAID use.Drugs like aspirin, ibuprofen, and naproxen (NSAIDs) may show to cause an increase in intestinal permeability.
- Supplement with probiotics. Probiotics’ beneficial bacteria may think to become beneficial for a variety of gastrointestinal conditions, including IBS.
- Reduce your level of stress. So, Chronic stress can harm gut bacteria.
- Consume less alcohol. Excessive alcohol consumption may increase intestinal permeability.
- Put an end to your smoking. Tobacco smoke may exacerbate digestive tract inflammation and is a risk factor for a variety of bowel conditions.
What to eat and what not?
Generally, we may get confuse and make bad choices when we have a leaky gut syndrome. That makes your condition far worse than it is. Therefore, making the correct choice of meal is quite essential. Hence, Not just this, you must also get all the knowledge about the bad food to avoid.
So, the food you should eat that will increase the bacterial diversity of your gut are:
- Eating a variety of fruits and vegetables such as zucchini, eggplants, broccoli, cabbage, and cauliflower
- Fruits like berries, oranges, grapes
- So, Nuts and seeds
- The lactose-free dairy products, including hard cheese, lactose-free milk, and plant-based dairy substitutes
- Grains like quinoa and oats
People who experience gastrointestinal symptoms should avoid these: